Preactivated thiomers: Evaluation of gastroretentive minitablets
نویسندگان
چکیده
منابع مشابه
Preparation and evaluation of gastroretentive floating tablets of Silymarin.
The present study performed by preparation and evaluation of floating tablets of Silymarin as model drug for prolongation of gastric residence time. Floating effervescent tablets were formulated by various materials like hydroxypropyl methylcellulose (HPMC) K 4M, K 15M, psyllium husk, swelling agent as crospovidone and microcrystalline cellulose and gas generating agent like sodium bicarbonate ...
متن کاملFormulation and Evaluation of Gastroretentive Floating Tablets of Domperidone Maleate
The low bioavailability (15%) and good solubility of Domperidone Maleate in acidic pH following oral administration favours development of a gastro retentive formulation. Gastroretentive floating matrix tablets of Domperidone Maleate were successfully prepared with hydrophilic polymers like HPMC K4M, HPMC K15M and HPMC K100M. From the Preformulation studies for drug excipients compatibility it ...
متن کاملDevelopment and evaluation of gastroretentive norfloxacin floating tablets.
Floating matrix tablets of norfloxacin were developed to prolong gastric residence time, leading to an increase in drug bioavailability. Tablets were prepared by the wet granulation technique, using polymers such as hydroxypropyl methylcellulose (HPMC K4M, HPMC K100M) and xanthan gum. Tablets were evaluated for their physical characteristics, viz., hardness, thickness, friability, and mass vari...
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ژورنال
عنوان ژورنال: International Journal of Pharmaceutics
سال: 2013
ISSN: 0378-5173
DOI: 10.1016/j.ijpharm.2013.08.032